COSAM » COSAM Faculty » Chemistry and Biochemistry » Bradley L. Merner

Bradley L. Merner
Chemistry and Biochemistry
S. D. and Karen H. Worley Associate Professor

Research Areas: Organic

Office: 362 Chemistry Building

Lab: 331 Chemistry Building

Phone: (334) 844-6910
Fax: (334) 844- 6959
E-Mail: blm0022@auburn.edu

Website


Education

Université de Montréal, Postdoctoral Fellow
2013
Memorial University, Ph.D
2010


Professional Employment

S. D. and Karen H. Worley Associate Professor
2019-present
James E. Land Assistant Professor
2016-2019
Assistant Professor, Department of Chemistry and Biochemistry, Auburn University
2013-2019
Post-Doctoral Research Associate, Université de Montréal
2009-2013


Honors and Awards

Chemical Communications Emerging Investigator
2020
S. D. and Karen H. Worley Professorship
2019
Thieme Chemistry Journal Award
2018
NSF CREER Award
2017
James E. Land Professorship
2016
Fellow of the School of Graduate Studies, Memorial University
2008
NSERC Postgraduate Scholarship: PGS D3
2005-2008
Memorial University School of Graduate Studies Dean's Excellence Award
2005-2008


Research and Teaching Interests

The central theme of our group’s research program is target-oriented chemical synthesis (vide infra).  Under this vastly defined area, our group will concentrate on the synthesis of architecturally complex molecules that are relevant to medicinal chemistry and nanoscale science.  We are interested in the synthesis of natural products, analogues thereof, nucleic acid modifications that can be used as gene silencing therapeutics, and curved aromatic systems that will serve as molecular templates in the bottom-up chemical synthesis of carbon nanotubes (CNTs).  Deeply rooted in all of the synthesis projects carried out in our laboratories will be the development of new synthetic technologies that address current weaknesses that exist in the arena of chemical synthesis.  It is hoped that this vision will facilitate the discovery of new, powerful synthetic disconnections that can ultimately be used to streamline synthetic approaches to bioactive compounds, enable analogue synthesis of more potent medicines, and improve the current state of the art for CNT synthesis.

tocs 

Graduate students interested in joining the group should apply directly to graduate program at Auburn University within the Department of Chemistry and Biochemistry.  Interested undergraduate students should send an E-mail to blm0022@auburn.edu or stop by my office to arrange a meeting.

All interested postdoctoral applications should include a current CV, copies of relevant publications, a concise summary of research experience (up to 5 pages), and at least two letters of recommendation sent under a separate cover.   These can be sent via E-mail to: blm0022@auburn.edu

 


Selected Publications

Mitra, N. K.; Corzo, H. H.; Merner, B. L. A Macrocyclic 1, 4-Diketone Enables the Synthesis of a p-Phenylene Ring that Is More Strained than [4] Cycloparaphenylene. Org. Lett. 2016, 18, 3278-3281.

Mitra, N. K.; Meudom, R.; Corzo, H. H.; Gorden, J. D.; Merner, B. L. Overcoming Strain-Induced Rearrangement Reactions: A Mild Dehydrative Aromatization Protocol for the Synthesis of Highly Distorted p-Phenylenes. J. Am. Chem. Soc. 2016, 138, 3235-3240

Mitra, N. K.; Meudom, R.; Gorden, J. D.; Merner, B. L. A Non-Cross-Coupling Approach to Arene-Bridged Macrocycles: Synthesis, Structure and Direct, Regioselective Functionalization of a Cycloparaphenylene Fragment. Org. Lett. 2015, 17, 2700-2703.
    - Selected as an ACS Editor’s Choice Article (May 8, 2015)
    - One of 10 most accessed articles for May 2015







Last updated: 10/22/2020