Publication

  1. W. Yang, Z. Zhang, C. Ma, Z. Gu, M. Witkowski, Y. Tian, E. A. Lipke, F. Ding, I. Aifantis, W. Chen, and P. Chen, "Nanoplasmonic Mapping of Single-Cell Cytokine Secretomic Signatures in CAR T-Cell Cancer Therapy," (in submission).

  2. J. He, S. Wu, W. Chen, A. Kim, W. Yang, C. Wang, Z. Gu, J. Shen, S. Dai, W. Chen, and P. Chen*, " Calligraphy of Nanoplasmonic Bioink-Based Multiplex Immunosensor for Precision Immune Monitoring and Modulation," ACS Appl. Mater. Interfaces (2023).
  3. M. Annaji, N. Mita, J. Heard, X. Kang, I. Poudel, O. Fasina, P. Baskaran, S. Boddu, A. Tiwar, P. Chen, C. Lyman, R. Babu *, " 3D‑Printed Capsaicin‑Loaded Injectable Implants for Targeted Delivery in Obese Patients," AAPS PharmSciTech (2023) 24:200.

  4. B. Ma, X. Liu, Z. Zhang, C. Ma, R. Chand, S. Patwardhan, C. Wang, S. Thamphiwatana, P. Chen, W. Chen*, " A digital nanoplasmonic microarray immunosensor for multiplexed cytokine monitoring during CAR T-cell therapy from a leukemia tumor microenvironment model," Biosens. Bioelectron. 230 (2023), 115247.

  5. F. Antony, X. Kang, C. Pundkar, C. Wang, A. Mishra, P. Chen, R. Babu, A. Suryawanshi *, " Targeting β-catenin using XAV939 nanoparticle promotes immunogenic cell death and suppresses conjunctival melanoma progression," International Journal of Pharmaceutics. 640 (2023), 123043.

  6. C. Pundkar, F. Antony, X. Kang, A. Mishra, R. Babu, P. Chen, F. Li, A. Suryawanshi *, " Targeting Wnt/β-catenin signaling using XAV939 nanoparticles in tumor microenvironment-conditioned macrophages promote immunogenicity," Heliyon. 9 (2023), e16688.

  7. X. Kang, S. Jadhav, M. Annaji, C. Huang, R. Amin, J. Shen, C. Ashby Jr, A. Tiwari, R. Babu*, P. Chen*, " Advancing Cancer Therapy with Copper/Disulfiram Nanomedicines and Drug Delivery Systems," Pharmaceutics. 2023, 15(6), 1567.

  8. X. Kang, Qi Wang, Siqi Wu, C. Wang, M. Annaji, C. Huang, J. Shen, P. Chen*, R. Babu* " Liposomal DQ in Combination with Copper Inhibits ARID1A Mutant Ovarian Cancer Growth," Biomolecules. 2023, 13(5), 744.

  9. L. Zhou, L. Liu, M. Chang, C. Ma, W. Chen, P. Chen*, "’Spatiotemporal dissection of tumor microenvironment via in situ sensing and monitoring in tumor-on-a-chip," Biosens. Bioelectron. 225 (2023), 115061.

  10. J. He, L. Zhou, G. Huang, J. Shen, W. Chen, C. Wang, A. Kim, Z. Zhang, W. Chen, S. Dai, F. Ding*, and P. Chen*, "Enhanced Label-Free Nanoplasmonic Cytokine Detection in SARS-CoV 2 Induced Inflammation Using Rationally Designed Peptide Aptamer," ACS Appl. Mater. Interfaces (2022).
  11. X. Kang, J. Wang, C. Huang, F. Wibowo, R. Amin, P. Chen, F. Li*, "Diethyldithiocarbamate Copper Nanoparticle Overcomes Resistance in Cancer Therapy without Inhibiting P-glycoprotein," Nanotechnol. Biol. Med. (2022).

  12. J. Shen, Z. Zheng, T. Dinh, C. Wang, M. Chen, P. Chen, Q. Ma, P. Herrero, L. Kang, S. Dai*, "Hyperbolic Phonon Polaritons with Positive and Negative Phase Velocities in Suspended α-MoO3," Appl. Phys. Lett. 120 (2022), 113101.

  13. Z. Gao*, C. Wang, J. He, P. Chen*, "Pd@Pt Nanodendrites as Peroxidase Nanomimics for Enhanced Colorimetric ELISA of Cytokines with Femtomolar Sensitivity," Chemosensors 10 (2022), 359.

  14. Z. Gao, Y. Song, T. Y. Hsiao, J. He, C. Wang, J. Shen, A. MacLachlan, S. Dai, B. H. Singer, K. Kurabayashi*, and P. Chen*, "Machine-Learning-Assisted Microfluidic Nanoplasmonic Digital Immunoassay for Cytokine Storm Profiling in COVID-19 Patients," ACS Nano 15 (2021), 18023.
  15. C. Wang, C. Huang, Z. Gao, J. Shen, J. He, A. MacLachlan, C. Ma, Y. Chang, W. Yang, Y. Cai, Y. Lou, S. Dai, W. Chen, F. Li*, and P. Chen*, "Nanoplasmonic Sandwich Immunoassay for Tumor-Derived Exosome Detection and Exosomal PD-L1 Profiling," ACS Sensors 6 (2021), 3308.
  16. X. Kang, Y. Cai, Q. Wang, C. Wang, W. Chen, W. Yang, A.Suryawanshi, G. Zhou, P. Chen, and F. Li*, "Near-Infrared Light Triggered Activation of Pro-Drug Combination Cancer Therapy and Induction of Immunogenic Cell Death," International Journal of Pharmaceutics 607 (2021), 120972.

  17. M. K. Brahma, E. H. Gilglioni, L. Zhou, E. Trepo, P. Chen, and E. N. Gurzov, "Oxidative Stress in Obesity-associated Hepatocellular Carcinoma: Sources, Signaling and Therapeutic Challenges," Oncogene (2021), 1-13.

  18. S. Du, I. Chen, A. MacLachlan, Y. Liu, T. Huang, Z. Cheng, P. Chen*, and B. A. Chin, "3D Phage-based Biomolecular Filter for Effective High Throughput Capture of Salmonella Typhimurium in Liquid Streams," Food Research International (2021), 110181.

  19. P. Chen, F. Ding, R. Cai, I. Javed, W. Yang, Z. Zhang, Y. Li, T. P. Davis, P. C. Ke, and C. Chen, "Amyloidosis Inhibition, a New Frontier of the Protein Corona," Nano Today , 35 (2020), 100937.
  20. C. Wang, Y. Cai, A. MacLachlan, and P. Chen*, "Novel Nanoplasmonic Structure based Integrated Microfluidic Biosensors for Label-Free in Situ Immune Functional Analysis," IEEE Nanotechnology Magazine 14(2020),46-C3.
  21. W. Yang, H. Veroniaina, X. Qi*, P. Chen*, F. Li*, and P. C. Ke, "Soft and Condensed Nanoparticles and Nanoformulations for Cancer Drug Delivery and Repurpose," Advanced Theraputics 3 (2020), 1900102.
  22. A. Faridi, W. Yang, H. G. Kelly, C. Wang, T. P. Davis*, P. Chen*, S. J. Kent*, and P. C. Ke*, "Differential Roles of Plasma Protein Corona on Immune Cell Association and Cytokine Secretion of Oligomeric and Fibrillar Beta-Amyloid," Biomacromolecules 20 (2019), 4208.
  23. Y. Chang, J. Jiang, W. Chen, W. Yang, L. Chen, P. Chen, J. Shen, S. Qian, T. Zhou, L. Wu, L. Hong, Y. Huang*, and F. Li*, "Biomimetic Metal-Organic Nanoparticles Prepared with a 3D-Printed Microfluidic Device as a Novel Formulation for Disulfiram-based Therapy Against Breast Cancer," Applied Materials Today (2019), 100492.

  24. Y. Cai, J. Zhu, J. He, W. Yang, C. Ma, F. Xiong, F. Li, W. Chen and P. Chen,"Magnet Patterned Superparamagnetic Fe3O4/Au Core-Shell Nanoplasmonic Sensing Array for Label-Free High Throughput Cytokine Immunoassay," Adv. Healthc. Mater 8 (2019), 1801478.
  25. I. Javed, J. He, A. Kakinen, A. Faridi, W. Yang, T. P. Davis, P. C. Ke, and P. Chen,"Probing the Aggregation and Immune Response of Human Islet Amyloid Polypeptide with Ligand-Stabilized Gold Nanoparticles," ACS Appl. Mater. Interfaces 11 (2019), 10462.
  26. W. Chen, W. Yang, P. Chen, Y. Huang, and F. Li, "Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers," ACS Appl. Mater. Interfaces. 10 (2018), 41118.
  27. J. Y. Zhu, J. He, M. Verano, A. T. Brimmo, A. Glia, M. A. Qasaimeh, P. Chen, J. O. Aleman and W. Chen, "An Integrated Adipose-Tissue-On-Chip Nanoplasmonic Biosensing Platform for Investigating Obesity-associated Inflammation," Lab on a Chip. 18 (2018), 3550.
  28. J. He, A. T. Brimmo, M. A. Qasaimeh, P. Chen, and W. Chen, "Recent Advances and Perspectives in Microfluidics-Based Single-Cell Biosensing Techniques," Small Methods 1 (2017), 1700192.
  29. X. W. Ge, A. Kakinen, E. N. Gurzov, W. Yang, L. Pang, E. H. Pilkington, P. Nedumpully-Govindan, P. Chen, F. Separovic, T. P. Davis, P. C. Ke, and F. Ding, "Zinc-Coordination and C-Peptide Complexation: A Mechanism for the Native Inhibition of IAPP Aggregation," Chem. Comm. 53 (2017), 9394. (Featured as front cover)
  30. Y. J. Song*, P. Chen*, M. T. Chuang, R. Nidetz, Y. Park, Z. H. Liu, W. McHugh, T. T. Cornell, J. Fu, and K. Kurabayashi, "AC Electroosmosis-Enhanced Nano-Plasmofluidic Detection of Ultra-Low-Concentration Cytokine," Nano Lett. 17 (2017), 2374. (* equal contribution)
  31. B. Ryu, H. Nam, B. R. Oh, Y. Song, P. Chen, Y. Park, W. Wan, K. Kurabayashi, and X. Liang, "Cyclewise Operation of Printed MoS2 Transistor Biosensors for Rapid Biomolecule Quantification at Femtomolar Levels," ACS Sensors 2 (2017), 274.

  32. B. R. Oh, P. Chen, R. Nidetz, W. McHugh, J. Fu, T. P. Shanley, T. T. Cornell, and K. Kurabayashi, "Multiplexed Nanoplasmonic Temporal Profiling of T-Cell Response under Immunomodulatory Agent Exposure," ACS Sensors 1 (2016), 941.
  33. E. N. Gurzov, B. Wang, E. H. Pilkington, P. Chen, A. Kakinen, W. J. Stanley, S. A. Litwak, E. G. Hanssen, T. P. Davis, F. Ding, and P. C. Ke, "Inhibition of hIAPP Amyloid Aggregation and Pancreatic beta-Cell Toxicity by OH-Terminated PAMAM Dendrimer," Small 12 (2016), 1615.

  34. P. N. Govindan, E. N. Gurzov, P. Chen, E. H. Pilkington, W. J. Stanley, S. A. Litwak, T. P. Davis, P. C. Ke, and F. Ding, "Graphene Oxide Inhibits hIAPP Amyloid Fibrillation and Toxicity in Insulin-Producing NIT-1 Cells," Phys. Chem. Chem. Phys. 18 (2016), 94.

  35. M. Chen, H. Nam, H. Rokni, S. Wi, J. S. Yoen, P. Chen, K. Kurabayashi, W. Lu, and X. Liang, "Nanoimprint-Assisted Shear Exfoliation (NASE) for Producing Multilayer Transition Metal Dichalcogenide Device Arrays," ACS Nano 9 (2015), 8773.

  36. P. Chen, N.-T. Huang, M. T. Chuang, T. T. Cornell, and K. Kurabayashi, "Label-free Cytokine Micro- and Nano-biosensing towards Personalized Medicine of Systemic Inflammatory Disorders," Adv. Drug Deliv. Rev. 95 (2015), 90.

  37. P. Chen, M. T. Chung, W. McHugh, R. Nidetz, Y. Li, J. Fu, T. T. Cornell, T. P. Shanley, and K. Kurabayashi, "Multiplex Serum Cytokine Immunoassay Using Nanoplasmonic Biosensor Microarrays," ACS Nano 9 (2015), 4173. (Featured by GenomeWeb, MICHR; Highlighted in Integrative Biology)
  38. B. Wang, S. A. Seabrook, P. Nedumpully-Govindan, P. Chen, H. Yin, L. Waddington, V. C. Epa, D. A. Winkler, J. K. Kirby, F. Ding, and P. C. Ke, "Thermostability and Reversibility of Silver Nanoparticle-Protein Binding," Phys. Chem. Chem. Phys. 17 (2015), 1728.

  39. H. Nam, B.-R. Oh, P. Chen, J. S. Yoen, S. Wi, M. Chen, K. Kurabayashi, and X. Liang, "Two Different Device Physics Principles for Operating MoS2 Transistor Biosensors with Femtomolar-Level Detection Limits," Appl. Phys. Lett. 107 (2015), 012105.

  40. H. Nam, B.-R. Oh, P. Chen, M. Chen, S. Wi, W. Wan, K. Kurabayashi, and X. Liang, "Multiple MoS2 Transistors for Sensing Molecule Interaction Kinetics," Sci. Rep. 5 (2015), 10546.

  41. P. Chen, S. A. Seabrook, V. C. Epa, J. Newman, K. Kurabayashi, A. S. Barnard, D. A. Winkler, J. K. Kirby, and P. C. Ke, "Contrasting Effects of Nanoparticle Binding on Protein Denaturation," J. Phys. Chem. C 118 (2014), 22069.
  42. B.-R. Oh, N.-T. Huang, W. Chen, J. H. Seo, P. Chen, T. T. Cornell, T. P. Shanley, J. Fu, and K. Kurabayashi, "Integrated Nanoplasmonic Sensing for Cellular Functional Immunoanalysis Using Human Blood," ACS Nano 8 (2014), 2667.

  43. Y. Wen, N. K. Geitner, R. Chen, F. Ding, P. Chen, R. E. Andorfer, P. N. Govindan, and P. C. Ke, "Binding of Cytoskeletal Proteins with Silver Nanoparticles," RSC Adv. 3 (2013), 22002.

  44. R. Li, R. Chen, P. Chen, Y. Wen, P. C. Ke, and S. S. Cho, "Computational and Experimental Characterizations of Silver Nanoparticle-Apolipoprotein Biocorona," J. Phys. Chem. B, 117 (2013), 43.

  45. S. Radic, N. K. Geitner, R. Podila, A. Kakinen, P. Chen, P. C. Ke, and F. Ding, "Competitive Binding of Natural Amphiphiles with Graphene Derivatives," Sci. Rep. 3 (2013), 2273.

  46. A. Kakinen, F. Ding, P. Chen, M. Mortimer, A. Kahru, and P. C. Ke, "Interaction of Firefly Luciferase and Silver Nanoparticles and Its Imapct on Enzyme Activity," Nanotechnology, 24 (2013), 34.

  47. F. Ding, S. Radic, R. Chen, P. Chen, N. K. Geitner, J. M. Brown, and P. C. Ke*, "Direct Observation of a Single Nanoparticle-Ubiquitin Corona Formation," Nanoscale 5 (2013), 9162.

  48. R. N. Urankar, R. M. Lust, E. Mann, P. Katwa, X. Wang, R. Podila, S.C. Hilderbrand, B. S. Harrison, P. Chen, P. C. Ke, A. M. Rao, J. M. Brown and C. J. Wingard, "Expansion of Cardiac Ischemia/Reperfusion Injury After Instillation of Three Forms of Multi-Walled Carbon Nanotubes," Part. Fibre Toxicol. 9 (2012), 38.

  49. P. Chen, B. Powell, M. Mortimer, and P. C. Ke, "Adaptive Interactions between Zinc Oxide Nanoparticles and Chlorella sp." Environ. Sci. Technol. 46 (2012), 12178.
  50. P. Bhattacharya, S. H. Kim, P. Chen, R. Chen, A. M. Spuches, J. M. Brown, M. H. Lamm, and P. C. Ke, "Dendrimer-Fullerenol Soft-Condensed Nanoassembly," J. Phys. Chem. C 116 (2012), 15775.

  51. X. Wang, P. Katwa, R. Podila, P. Chen, P.C. Ke, A. M. Rao, D. M. Walters, C. J. Wingard, and J. M. Brown, "Multi-Walled Carbon Nanotube Instillation Impairs Pulmonary Function in C57BL/6 Mice," Part. Fibre Toxicol. 8 (2011), 24.

  52. P. Chen, Y. Yang, P. Bhattacharya, P. Wang, and P. C. Ke, "A Tris-Dendrimer for Hosting Diverse Chemical Species," J. Phys. Chem. C 115 (2011), 12789.
  53. K. Lingam, R. Podila, C. Loebick, P. Chen, P. C. Ke, B. Powell, L. Pfefferle and A. M. Rao, "Effect of Bundling on the Pi-Plasmon Energy in Sub-Nanometer Single Walled Carbon Nanotubes," Carbon 49 (2011), 3803.

  54. I. Huizar, A. Malur, Y. A. Midgette, C. Kukoly, P. Chen, P. C. Ke, R. Podia, A. M. Rao, C. J. Wingard, L. Dobbs, B. P. Barna, M. S. Kavuru, and M. J. Thomassen, "Novel Murine Model of Chronic Granulomatous Lung Inflammation Elicited by Carbon Nanotubes," Am. J. Respir. Cell Mol. Biol. 45 (2011), 858.

  55. R. Podila, P. Chen, J. Reppert, A. M. Rao, and P. C. Ke, "Biomolecular Sensing Using Gold Nanoparticle-Coated ZnO Nanotetrapods," J Mater. Research 26 (2011), 2328.

  56. P. Bhattacharya, P. Chen, M. N. Spano, L. Zhu, and P. C. Ke, "Copper Detection Utilizing Dendrimer and Gold Nanowire-Induced Surface Plasmon Resonance," J. Appl. Phys. 109 (2011), 014911.

  57. P. Chen, Q. Gan, F. Bartoli, and L. Zhu, "Spoof Surface Plasmon Assisted Light Beaming in Mid-infrared," J. Opt. Soc. Am. B 27, (2010) 685.

  58. P. Chen, Q. Gan, F. Bartoli, and L. Zhu, "Near Field Resonance Enhanced Plasmonic Light Beaming," IEEE Photonics J. 2, (2010) 8.