Why This Matters
March 5, 2026 | Asia White, PharmD Candidate 2026
Many people use over-the-counter (OTC) products for colds, pain, allergies, or low energy without realizing that some ingredients can raise blood pressure. This can be especially important for people who already have high blood pressure or take medications to control it. Even short-term use of certain products may cause blood pressure to increase. Taking a moment to read labels can help prevent problems.
Cold, flu, and allergy products with decongestants
Decongestants relieve a stuffy nose by shrinking blood vessels in the nose. This same effect can raise blood pressure by tightening blood vessels throughout the body. People with high blood pressure should use caution with these products.
- Common decongestants on labels are Pseudoephedrine and Phenylephrine.
- These ingredients are often found in combination cold and sinus products.
- Helpful tip: If a product name ends with a “D,” it often contains a decongestant. Always check the Drug Facts label.
- Safer options for congestion are saline nasal spray or rinse, humidifier or steam, rest and fluids.
Pain relievers that may raise blood pressure
- Certain pain relievers can raise blood pressure, especially when used often. These medications can cause the body to retain fluids, which may increase blood pressure and strain the heart and kidneys.
- Pain relievers to watch for are Ibuprofen and Naproxen. These medications belong to a group called NSAIDs.
Safer use tips
- Use the lowest effective dose for the shortest amount of time.
- Avoid daily or long-term use unless directed by a healthcare provider.
- Monitor blood pressure while using these products.
- Stop the medication and contact a pharmacist or healthcare provider if blood pressure increases.
- Ask a pharmacist or healthcare provider about pain relievers that are not NSAIDs.
- When possible, try non-medication options such as rest, ice or heat, gentle stretching, or staying well hydrated.
Caffeine and energy products
- Caffeine can cause a short-term increase in blood pressure, especially in people who do not use caffeine regularly.
- Products that may contain caffeine include energy drinks or shots, pre-workout supplements, and some headache or cold products.
- Check labels and avoid combining multiple caffeine-containing products in one day.
Herbal and natural products
Some herbal supplements may raise blood pressure or interfere with blood pressure medications. Examples include licorice, ginseng, and guarana. Always tell your pharmacist or healthcare provider about any supplements you use.
How to quickly check a label
Before taking an over-the-counter product:
- Read the Drug Facts box.
- Check the active ingredients.
- Watch for decongestants, NSAIDs, or caffeine.
- Review the warnings section.
- Ask a pharmacist if you are unsure which product is safest.
When to ask for help
- Talk to a pharmacist or healthcare provider if blood pressure rises after starting a new product, if you are unsure what is safe with your medications, or if you need symptom relief and have high blood pressure.
- Seek urgent care for chest pain, severe shortness of breath, fainting, or stroke warning signs such as facial drooping, weakness, or trouble speaking.
References
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Mayo Clinic. High blood pressure and cold remedies: Which are safe? Mayo Clinic website. Updated April 15, 2024. Accessed January 28, 2026.
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American Heart Association. Over-the-counter medications and high blood pressure. American Heart Association website. Updated August 14, 2025. Accessed January 28, 2026.
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MedlinePlus. High blood pressure—medicine-related. MedlinePlus, U.S. National Library of Medicine website. Updated October 27, 2024. Accessed January 28, 2026.